The accuracy of colposcopy has been questioned in some recent studies. The aim of
the study was to to evaluate the overall perfect agreement, underestimation and
overestimation rate between colposcopically directed biopsies and the definitive
excisional specimens in different age groups.
In a retrospective study of 456 patients who underwent conization within 6 months after
colposcopy directed cervical biopsy were included. The most severe pathological result
for both cervical biopsy and conization specimen were used for comparison. The
patients were divided into three groups according to their age: under 30 years,
between 30-50 years of age and over 50 years of age. The overall perfect agreement,
underestimation and overestimation rates were compared among these age groups.
Overall perfect agreement, underestimation and overestimation rates between
pathological results of colposcopy directed biopsies and cervical conization were
50.4%, 16.0% and 33.6% respectively. Overall perfect agement for CIN1, CIN2 and
CIN3/CIS/AIS were 55.2%, 27.6%, 71.7% respectively. Overall perfect agreement
rates of under 30 years of age, between 30-50 years of age and above 50 years of age
were 54.2%, 52.8%, 35.9% respectively. There was lower overall perfect agreement
rate of in above 50 years of age group.
Our results confirm that the safety of colposcopy is less reliable in women older than
50 years. It has a relatively high accuracy for the diagnosis of cervical CIN3/CIS/AIS
and MIC lessions.
Anahtar Kelimeler: Cervical Intraepithelial Neoplasia, Conization, Colposcopy